Form the Honda site:
Honda engines are certified and designed to run on regular unleaded gasoline.
Gasoline is allowed, by regulation, to contain a variety of additives. The same regulation limits how much of some additives, such as alcohol, can be included in the fuel and still be sold as gasoline. Honda engines are designed for good performance and efficient operation using gasoline containing from 0 to 10% ethanol.
E85 is an alternative fuel. It is not gasoline. It is made by combining 85% ethanol with 15% gasoline. Honda engines are not currently certified or designed to run on E85 or any other alternative fuel.