According to Asus' CPU compatibility list
, it is supported as long as you've got BIOS 0813 or better installed. If your BIOS is older than that, make sure you flash the BIOS *before* replacing the CPU.
What CPU do you have now? If you've already got a high-end Phenom II the FX-8150 may not be much of an upgrade (or could even be a downgrade if your workload can't take advantage of the 8 cores).