Well, the SSD doesn't care if it is defragged or not, and seriously, for a Windows boot drive, it won't stay that way long anyway.
But yes, Macrium has been very reliable here, and even helped me upgrade my Asus laptop from 500 GB to two 1TB drives. The bare bones prep from a backup image worked flawlessly, and the only time I have trouble with my scheduled backups is when the destination drive is full or if I forgot to plug it in...d'oh!
Macrium is highly recommended here. So well done that I left Acronis True Image by the side of the road, wilting in the hot sun. Although I still use Acronis Disk Director whenever partitions need to be mangled with.