It's not that compartmentalization is a bad idea -- it isn't; rather, it's the method, or logistics of compartmentalization that is the issue. Having a computer design with absolute minimalist graphics output but with an external link directly to 32-lanes of PCI/e 2.0 in one chassis (or compartment) and a self-contained (and separately-powered & cooled) high-end graphics subsystem in a second chassis (or compartment) seems to be the ideal compromise. Alternately, using a single chassis, having air-flow zones seems to be the better design.
While the Thermaltake multi-compartment modular chassis is a neat, futuristic concept case, it really isn't very practical. I must admit, although I would never buy it, I like it a whole lot better than Lian-Li's Dubai Tower case. The Thermaltake case looks high-tech cool whereas the Lian-Li just looks strange.
pc-v600b, ss-860xp, max V gene, 3770k, 4x8gb ddr3 2400, i520 240gb ssd (os/apps), i520 480gb ssd (workspace), 2x3tb wd30efrx (raid-1) & i525 60gb ssd (cache), 2x GV-R795WF3-3GD, 2x u3014, leopold/cherry brown kb, g400, intuos5 pth650, win.7.x64.ult