During installation, you can move the entire Users folder. Useful if you have a small SSD being used as the OS drive, or if you intend to install a lot of large programs. Google for this, there's various posts on the sevenforums about it. Moving the Users folder to the HDD in turn moves AppData, Desktop, Documents, etc. I'd also recommend moving ProgramData to the HDD as well. Apparently, you can also move Program Files / Program Files (x86) but apparently, doing so can get buggy results, so I'd install programs manually to the HDD. (And deal with what's left that stays on the SSD? I guess.)
If the SSD is too small you have to go that extreme, but I would say moving Downloads, Documents, Music, Pictures, and Videos (may be Favorites, but .url files are small) should be enough. The temp folder(s) is where the SSD help with the experience. Think about it, all your browser caches run off the SSD, which should be lightning fast. IMO it defeats the purpose moving all the stuff back to mechanical.
Small OS drives (i.e. SSD's) + HDD's + Windows 7 = One giant mess. Good luck.
Organization, management, and decision making. I don't think it is that messy at all. OTOH, we don't need to pinch so much money just to get a 40gig drive anymore, so that makes it less messy.
I'd skip the clutter crap on the web like disabling pagefile and hibernation. Half the point of getting an SSD is to speed up paging and hibernation processes. Obviously though, you want TRIM set appropriately, defragmentation and indexing disabled, etc.
Using a modern enough OS should automatically detect the SSD and set those properly. Disabling indexing is debatable, as linked from a previous post.
The Model M is not for the faint of heart. You either like them or hate them.
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