Unless you're looking at enterprise (server) gear, Linux generally is NOT officially supported. You'd probably get pretty much the same answer from Asus, MSI, ASRock, or any of the other motherboard vendors.
That said, just because it isn't officially supported doesn't mean it won't work. In general, motherboards "just work" with Linux whether it is officially supported or not. You can test this by booting a live Linux image from a USB stick.
The most likely area to run into Linux motherboard compatibility issues is with voltage/temperature monitoring and fan control. Support for the various sensors and fan headers can be very hit-or-miss. Most BIOSes have fairly reasonable built-in fan controls these days; I generally just set a fan profile in the BIOS and don't worry about it. So it'll probably come down to how much you care about being able to check system voltages and temperatures from within the OS.
Nostalgia isn't what it used to be.