No problem. I'm using a 7950GT to run Eve online and Valve games. It pushes 1900x1200 with high(ish) settings at good frame rates. The only thing I noticed in games that bothered me a couple times was a situation where there were vertical lines (say a pillar in front of a building in TF2). If you moved your view quickly horizontally, the vertical sides of the pillar would look more like a stair case during the rapid movement. This is referred to as "tearing". I believe I turned on V-sync and the effect was gone.
If you've been using LCDs to game, it probably won't be an issue for you either way. But if you're moving from CRT like I did, it is a bit unnerving at first, since you are so used to the fluid motion of a CRT. Since V-sync fixed it for me, I was satisfied.
I don't really have any complaints once I got that resolved.
If you get it, I advise the following settings:
That works very well in daylight and at night, and represents color accurately (significantly more so than the defaults). It is a *VERY* bright monitor, so anything over 30 brightness would be total overkill. It's not a linear scale so there is a "jump" in brightness at 31.
Like I said though, if you've got $600 to spend on a monitor, I really recommend getting their 0-pixel guarantee, and when you get the monitor, download any freeware pixel tester (they basically blank out the screen in red, black, white, blue, etc.) and see if you get dead pixels on particular colors.