5400x1920 @ 120 Hz, that's 10.4 megapixels.
I was able to drive my puny 2560x1600 (4.1 megapixel) display with decent GW2 performance at maximum settings with a single Radeon HD6970. My PC was pulling over 400 watts from the UPS and there was a lot of heat being discharged from the case while I was playing, but it played pretty decently. I didn't check the frame rate, but I'm certain that it was less than 60 fps.
i7-6700K, NT06-Pro, GA-Z170N-Gaming5, 32 GiB, RX Vega56, SM951, 5TB HDD, Blu-ray, FTZ01, SX600-G, C32HG70, RK-9000BR, MX518