Researchers concluded that the pain receptors don't secrete enough neuropeptides — chemical elements found in the brain — to keep the pancreatic islets, which produce insulin, working normally. Without insulin, humans die, and even the current replacement therapies cannot prevent side effects, such as heart attack, blindness, stroke, loss of limbs and kidney failure.These findings apply to Type One diabetes, but the researchers believe the findings could also be used to treat Type Two diabetes. For now, the researchers are reportedly working to extend their testing to humans.
But by supplying neuropeptides to diabetes-prone mice, "the research group learned how to treat the abnormality . . . and even reversed established diabetes," without bad side effects, [a press release published earlier this week] said.