For my testing, I mated the Nepton 240M to my version of TR's Casewarmer, which is built around an AMD A10-7850K processor with a 95W thermal envelope. The 7850K is installed in a Socket FM2+ motherboard, the MSI A88XI AC.
While the Nepton 240M's mounting hardware differs from socket to socket, the process starts with a universal backplate. The rest of the pieces for each specific socket type are mounted on top of this plate.
First, I clipped the appropriate quartet of bolts to the universal backplate before threading them through the mounting holes in the motherboard. I then secured the backplate to the motherboard using the four female-female nuts provided. This solution is much better thought-out than the Seidon 120V's. That cooler's mounting bracket is free to fall back out of the motherboard at this stage. The Nepton 240M's intermediate nuts also provide a more solid foundation for the water block. The Seidon 120V's pump can twist around on the processor if too much stress is placed on the coolant hoses, since there's nothing directly securing the bracket to the motherboard.
Next, I secured the proper brackets for AMD sockets to the pump block with four screws. This process is a little more involved than it is with the Seidon 120V, whose mounting bracket simply slips over the top of the water block.
After applying the included thermal paste to the processor's heat spreader, I screwed each of the four spring-loaded bolts into their complementary nuts, using the star pattern suggested by the manual to achieve an even clamping force.
As you can see above, the Nepton 240M is a very tight fit on the A88XI AC (and probably other mini-ITX motherboards, as well). The fittings for the pump clear the RAM by about half a millimeter. If you're thinking about a Nepton for your mini-ITX build, be very careful about the RAM you choose. The Nepton's pump might run into over-wide heatspreaders.
Finally, I mounted the system inside my testbed case, the Corsair Carbide Series Air 240. (Keep an eye out for my review of this case soon.) I set up the fans as intakes to ensure the CPU would be cooled by the freshest air possible.
I tried to mount the radiator using the rubber vibration-dampening gasket, but keeping the fan-gasket-radiator sandwich together during installation proved impossible. In the end, I set the gasket aside. Builders setting up the Nepton 240M with the fans on exhaust duty will probably have an easier time.
Let's now fire up Prime95 and see how the Nepton handles the A10-7850K switching away beneath its water block.